Effect of Pedicoccus acidilactici on immunity, production and lipid profile in broilers

The present study was conducted to investigate the effect of Pedicoccus acidi lacti supplementation to the ration of broiler chicks on growth performance, survival rate, immunity, hematological studied, serum biochemistry, response to NDV and its protective effect against artificial infection with S. enteritidis . One hundred and twenty day-old broiler chicks were allotted into four equal groups: group one fed on non- supplemented ration and not infected, group two fed on ration contain Pedicoccus acidi lacti 100 mg/kg ration and not infected, group three fed on non- supplemented ration and infected and group four fed on ration contain Pedicoccus acidi lacti 100 mg/kg ration and infected with salmonella. The results indicated that Pedicoccus acidi lacti supplementation improved the body weight and FCR in comparison to control group during the first two weeks [pre-infection], After infection the results indicated that the Pedicoccus acidi lacti supplementation protect chickens against bad effect of salmonella infection where both parameter [FCR and Body weights] still superior till 5th week. Also the addition of probiotics improved lipid profile and CBC. In the same time. It was evident that addition of Pedicoccus acidi lacti improved immune response to ND

Pesticide exposure as a risk factor for lymphoproliferative disorders in adults

In view of the widespread use of pesticides in Egypt and the increasing incidence of leukaemia and lymphoma we aimed to assess pesticide exposure and other selected variables as risk factors for lymphoproliferative disorders [leukaemia and non-Hodgkin lymphoma]. In a hospital-based, retrospective, case-control study in 2011-2012, adult cases of lymphoproliferative disorders [n = 130] were recruited from outpatient clinics in Menoufia, Egypt, while controls [n = 130] were age- and sex-matched fracture patients. Family history of cancer, exposure to X-rays, smoking and use of hair dyes were not risk factors for lymphoproliferative disorders in univariate analysis. History of exposure to pesticides and HCV infection were significant risk factors for lymphoproliferative disorders in multivariate analysis [OR = 2.24; 95% CI: 1.22-4.11 and OR = 2.67; 95% CI: 1.50-4.80 respectively]. The risk was significant for cases of non-Hodgkin lymphoma but not chronic lymphocytic leukaemia

Study of fingerprints pattern among some saudis of different ABO blood groups

Fingerprint evidence is undoubtedly the most reliable and acceptable evidence till date in the court of law. Due to the immense potential of fingerprints as an effective method of identification an attempt has been made in the present work to: 1- Study the distribution of fingerprint pattern among the participants having different ABO and Rh blood groups. 2- Study any relationship between their characters and blood groups. A cross-sectional study was conducted on 310 male students aged from 22-30 years in the first grade of the King-Fahad Security College Riyadh, Saudi Arabia. This study was carried out over a period of 3 months from March to May 2011. The plain fingerprints of all the ten digits were taken separately on the respective blocks on the sheet of paper. The details of their blood group were registered from their college identity cards. Statistical analysis of the obtained data showed that the majority of the subjects [54.5%] in the study were of blood group O followed by blood group A [28.8%], then blood group B [13.5%] and AB [3.2%]. Rh positive cases constituted about [91.9%] of all the studied cases. The general distribution pattern of fingerprints showed high frequency of loops[48.1%] followed by whorls [47.0%] and arches [4.9%]. There was a statistical significant difference among blood groups as regards pattern of fingerprints. Whorls were the commonest type of fingerprints in participants with blood groups A [48.3%], B[54.0%] and AB [59.0%] while, loops were the predominant pattern among participants with blood group O [50.2%]. Whorls are the predominant pattern of fingerprints in participants with Rh positive and Rh negative blood groups A [47.8% and 53.8%], B [54.9% and 48.0%], AB [56.3% and 70.0%] respectively and in Rh negative blood group O [53.0%]. Otherwise loops predominated in Rh positive blood group O [50.6%].Whorls were the most frequent fingerprint pattern in all types of ABO blood groups as regards ring, index and thumb fingers. The total fingers ridges count [TFRC] was significantly greater in blood group O. The study suggests relationship between fingerprints pattern and blood groups. We recommend further studies to be done on larger samples

Surgical Management of Ipsilateral Fracture of the Femur and Tibia in Adults (the Floating Knee): Postoperative Clinical, Radiological, and Functional Outcomes

BACKGROUND: This study evaluated the outcomes of surgical management of ipsilateral femoral and tibial fractures in adults. METHODS: Fifteen patients (13 men, 2 women; mean age, 34.8 years; range, 18 to 65 years) were enrolled in this study. The fractures types were classified according to the classification by Fraser et al. as follows: type I (5), type IIa (3), IIb (4), IIc (3). Femur fractures were treated using locked intramedullary nails, plate-screws, or dynamic condylar screws, and tibia fractures were treated with an external fixator (in open fractures), or plate-screws, and locked intramedullary nailing. The mean follow-up duration was 2.2 years (range, 1.3 to 4 years). RESULTS: The extent of bony union according to the Karlstrom criteria was as follows: excellent, 8; good, 4; acceptable, 2; poor, 1. CONCLUSIONS: The associated injuries and type of fracture (open, intra-articular, comminution) are prognostic factors in a floating knee. The best management of the associated injuries for good final outcome involves intramedullary nailing of both the fractures and postoperative rehabilitation.

Factors affecting quality of life for patients with rectal cancer undergoing radiotherapy

Rectal cancer is a significant health problem for patient and results in bowel and sexual function problems. Quality of life is an important outcome measure that has to be considered when deciding treatment strategy for rectal cancer. It has become an integral part of the modern assessment of cancer treatment. This study has been conducted to assess the factors affecting quality of life for patients with rectal cancer undergoing radiotherapy. A descriptive exploratory study was conducted at the surgical outpatient's clinics and Radiotherapy and Nuclear Medicine Department in Ain Shams University Hospitals. A purposive sample of 50 adult patients from both sexes with rectal cancer undergoing radiotherapy were recruited for the conduction of this study, from the above mentioned setting. [1] Patients' interview questionnaire sheet were used to assess factors affecting quality of life [pre treatment course, during radiotherapy and pre surgery], [2] Quality of Life Scale that was used to assess the impact of rectal cancer on the quality of life dimension [physical, psychological, social and spiritual] for the patients during and after radiotherapy and [3] A self-report 5 day diary to identify patients' complications during radiotherapy sessions. The prominent factors affecting on quality of life were patients' age and education, disease stage, side-effects, physical condition and nature of the surgery. There were statistically significant differences between the side-effects during and after radiotherapy, added to the improvement in physical and psychological domains of quality of life post radiotherapy by one month later. There were many factors affecting on quality of life for patients with rectal cancer undergoing radiotherapy [pre treatment course, during radiotherapy and pre surgery]. In addition strong positive correlation was found regarding to these factors and quality of life domains. Further studies are needed to focus on other factors affecting on quality of life for patients with rectal cancer undergoing chemotherapy

Perception of patients for their biopsycosocial status, subjected to total hip replacement

Total hip replacement is a one of the most common surgical procedures in the world among elder patients. This surgical procedure has been effective in relieving patients' pain and improving their walking ability of this study was to assess the perception of patients subjected to total hip replacement for their biopsychosocial status. This study was conducted at the orthopedic department and clinical out patients in Eldmerdash surgical hospital which is affiliated to Ain Shams University. A purposive sample of [77 patients] adult and old age from both genders with were recruited for the conduction of this study. Tools: I] patient's interviewing questionnaire sheet to assess Socio-demographic characteristics, past and present history and patients' information about total hip replacement .2] Patients' perception assessment sheet to assess their perception as regard biopsycosocial status before and after the surgery, and 3] Neurovascular assessment sheet to evaluate the neurological and vascular integrity of the affected limb before and after the surgery. The present study revealed that more than half of the patients were female and illiterate. There was a significant difference as regards patients' positive perception as well as neurovascular assessment before and after the surgery. Significant improvement was found in the perception of patients subjected to total hip for their biopsycosocial status [physical, psychological, social and spiritual] after the surgery. Furthers study should be designed to study the impact of perception on quality of life of patients subjected to hip replacement

Efficacy of self - care practices on promoting quality of life of diabetic women with menopausal symptoms

This study aims to assess the efficacy of Self - care practices on promoting quality of life of diabetic women with menopausal symptoms. A quasi - experimental design was used. The study was carried out in diabetic clinics of Maternity Hospital and Ain Shams University Hospital, affiliated to Ain Shams University. A purposive sample included 130 diabetic women with the age above 40 years, visiting the diabetic clinic over a period of three months. Tools: 1] An interviewing questionnaire sheet [pre / post tests] to determine women's knowledge about Self - care practices during menopause, 2] Menopausal symptoms assessment sheet [pre / post tests] and 3] An observation check list [pre / post tests], to assess women's practical skills regarding to self care. There are statistically significant differences between women's knowledge and practices in pre / post tests added to significant reduction in the menopausal symptoms disturbances in post test, which reveals women's QOL improvement. Acquisition of self - care practices through training intervention were helpful in promoting QOL for diabetic women with menopausal symptoms. Training sessions about self care practices during menopause should be generalized for the diabetic women. Further studies are required to study the effect of menopausal symptoms on the women's activities of daily living

Enhancing nurses ' competency to maintain technologic devices at critical care units

The danger in critical care units technology and unplanned device removal presents a different life threatening scenario and tremendous burden for the nurses. Maintaining technologic access was the core problem identified in this study. This study aims to assess the enhancing nurses competency to maintain technologic devices at critical care units. A quasi experimental design was used. This study was carried out at critical care units of El-Demerdash Hospital [General Surgery] and Children hospital, affiliated to Ain Shams University. A purposive sample composed of 65 nurses, 25 were caring for children and rest of them 40 were caring for adults, and 45 critically ill patients [28 adult and 17 children] added to 22 physician from the above mentioned settings. Tools: 1] Self administered questionnaire to assess nurses' knowledge [pre/post tests], 2] An observation checklist to assess nurses practice [pre/post tests], 3] Patients assessment sheet [pre/post tests], and 4] Opinnionair sheet for physicians and nurses [pre test]. There are statistically significant differences between nurses' knowledge and practice in pre/post tests regarding to technologic devices maintenance at critical care units, added to significant reduction in the percentage of removing technologic devices among the studied patients in post tests. Enhancing nurses' competency through training program was helpful to maintain technologic devices at critical care units . Educational program should be held periodically for critical care nurses about technologic device maintenance. Further studies should be done to assess the long term effects of such program on patient's quality of life at the critical care units

Drug resistance evaluation of some commonly used anti-coccidial drugs in broiler chickens

The study investigated some anticoccidial resistance for Amprol, Toltrazuril and sulfaclozine in experimental infected broiler. Eimeria identification depended on necropsy and coproscopic examination. 140 day-old chicks allotted into 7 groups and infected with Eimeria in 2[nd] day of age. G1: neither infected nor treated [negative control], G2: infected but not treated [positive control], Infected and treated with toltrazuril [G3], or with Amprol+Allicin [G4], or with Amprol+ethobabate [G5], or with Amprol [G6] or with Sulfaclozine [G7]. Eimeria infection caused decrease in body gain, total protein, albumin but increase in FCR, ALT, AST, Uric acid, Creatinine. Treatment decreased the harmful effect of infection but some significant differences were between infected treated groups and non infected non-treated one

Ultrasound-guided internal jugular vein cannulation versus blind technique in pediatric cancer patients

Percutaneous Cannulation of the internal jugular vein in infants and children is technically more difficult and carries a higher risk of complication than in adults. The authors tested their hypothesis that using an ultrasound scanner would increase the success of internal jugular Cannulation and decrease the incidence of complication in pediatric cancer patients. After approval from the hospital ethical committee [75375 hospital] and receipt of written informed parental consent, 108 children scheduled for internal jugular vein Cannulation were randomized into two groups; landmark group using the traditional method and ultrasound group, using sonography guidance for insertion. The access time, number of attempts, success rate, and incidence of complications were compared for the two groups. There were no significant differences between the two groups with regard to age, sex, weight and coagulation profile. The success rate was 98.1% in the ultrasound group, with one case of carotid artery puncture, versus 85.2% in the landmark group, with a 14.8% incidence of carotid artery puncture. Both differences were significant [p<0.001]. The access time was less, the number of attempts was fewer significantly in the ultrasound group than in the landmark group. No cases of hemothorax or pneumothorax occurred in this group. Ultrasonographic localization of the internal jugular vein was superior to the landmark technique in terms of overall success, speed and decreased incidence of complication

Examination of the sclerotomy sites after pars plana vitrectomy by ultrasound biomicroscopy

This present study aimed at studying different changes that could occur at the sclerotomy sites following pars plana vitrectomy by the use of ultrasound biomicroscopy. Ultrasound biomicroscopy [UBM] was used for examinations of slcerotomy sites in 60 eyes of 60 patients after pars plana vitrectomy. Different ultrasound biomicroscopic characteristics for these patients 8-10 weeks post operatively ranging from complete healing, gaping to fibrovascular proliferation. UBM is helpful in detecting complications at the sclerotomy sites after pars plana vitrectomy

Hyperbaric oxygen therapy: effect of intervention guidelines on knowledge and practices of patients with chronic wounds

Hyperbaric oxygen therapy [HBOT] is an important adjunct in the management of wound problems, which exist in chronic oxygen deficiency and in which the local oxygen tension is below optimal of healing. This study aims to evaluate the effect of HBOT intervention guidelines on knowledge and practices of patients with chronic wounds. A quasi experimental design was used. This study was conducted at the Hyperbaric Oxygen Therapy Unit, affiliated to Naser Institute Hospital. A purposive sample included 40 adult patients with chronic wounds [Diabetic foot ulcers, venous leg ulcers and pressure ulcers]. 1] Patients' interviewing questionnaire sheet to assess patients' knowledge [pre/post tests], 2] An observation checklist to evaluate patient's practices [pre/post tests], 3] Anxiety Rating Scale to determine patients' anxiety level [pre/post tests], 4] Developed guidelines, 5] Patient condition assessment: wound symptoms chart to assess symptoms experienced by the patients, and wound assessment parameter scoring tool to assess wound healing [pre/post treatment]. There is a lack of knowledge and practices among the study sample. Statistically significant differences were also found between pre/post guidelines regarding to their knowledge and practices in relation to HBOT. In addition, patients had a higher level of anxiety in the pre test, while it decreased in post tests. The HBOT intervention guidelines were helpful on the improvement of knowledge and practices of the patients with chronic wounds. There is a need for sustained patients' educational sessions, HBOT should be available for all patients with chronic wounds. Further studies should be done on a large number of subjects for evidence of results and generalization

Day case cataract surgery: improving patients self-care practices

This study aims to assessing improving self care practices for patients having day case cataract surgery. An experimental design was used. This study was conducted at the outpatient clinics in Ain Shams University Hospital and Research Institute of Ophthalmology. A purposive sample included 80 adult patients having day case cataract surgery from the aforementioned settings, categorized into study group [n=40] and control group [n=40]. 1] Patients' interviewing questionnaire sheet [pre/post assessment], 2] An observation checklist [pre/ post assessment], 3] Psychometric assessment tool [pre/post assessment] and 4] Patients condition assessment sheets [post-assessment]. There are significant differences between patients' knowledge and practices in pre/post and follow-up tests regarding to cataract surgery and self-care. Significant improvement was indicated in post-test. The study group had a higher mean score than the control group. The improving in self care practices through training intervention was helpful for patients having day case cataract surgery. Further studies are needed to elucidate the effect of training intervention on preventing post operative complications in day case cataract surgery

Efficacy of technical nursing concern on prevention and management of pressure ulcers

This study aims to evaluate the efficacy of technical nursing concern on prevention and management of pressure ulcers. A quasi-experimental design was used in the conduction of this study as a research methodology. The study was conducted in the following units [oncology, intensive care, orthopedic, neurological and bum at children hospital, Ain Shams Hospital, El-Demerdash Hospital, El-Mataria Hospital and New Children Hospital. A purposive sample included 100 pediatric nurses, 80 medical-surgical nurses, 75 child aged from 6-18 years plus 50 adult patients without pressure ulcers at admission and 50 child plus 50 adult patients having ulcers from the aforementioned settings. Different tools were used for data collection [pre/post tests]; 1] Self-administered questionnaire to assess nurses' knowledge, 2] An observation checklist to assess nurses' practice, 3] The Braden scale for predicting risk of pressure ulcers; 4] Pressure ulcers assessment scale and 5] Pressure ulcers healing scale. The study revealed that there were highly statistically significant differences between knowledge and practice of nurses in different settings about pressure ulcers [prevention and management] in pre/ post tests. Increasing technical nursing concern through educational program had a positive effect on prevention and management of pressure ulcers. The educational programs and workshops about pressure ulcers [prevention and management] are needed. Further studies are needed to shed light on non-traditional methods of pressure ulcers management

Biological evaluation of some modified snacks

This investigation aims to assess the effect on health of some modified snacks prepared by addition of different food items known to be rich either in protein or compounds with health value. A basic formula based on snacks available in the local market was modified by adding each of eggs, whey protein, chickpea, soybean, wheat germ, carrot, orange peel or strawberry. The modified products were evaluated through assessment of their effect on lipid pattern and possible atherosclerosis by following the level of plasma total cholesterol and triglycerides, the state of oxidation stress through estimation of R.B.C's malondialdehyde [MDA] and plasma superoxide dismutase enzyme activity [SOD] and the state of the liver and bile duct through determining the level of gamma -glutamyl transferase [gamma -GT]. Groups of rats were given either the basic formula of snack or the modified ones together with a selectively high cholesterol level. It was observed that the modified formulas succeeded to protect against the increase in plasma cholesterol and triglycerides. Also they protect against the state of oxidation stress confirmed by decreased MDA level and with no hazard on the liver indicated by the normal or even low activity of gamma -GT. It is concluded that snacks available in the local market can be modified to better ones through addition of different food items. The modified snacks are of high protein content and can protect against hyperlipidemia and oxidation stress with no harmful effect on liver

Protein profile and morphometry of cultured human blastocystis hominis from children with gastroenteritis and healthy ones

A total of 180 children of age group 5-12 years old in both sexes, of whom 90 were symptomatic and negative for other parasites, rota-virus or pathogenic bacteria. Another 90 children were asymptomatic, but with B. hominis in stools. Direct smear, formaline-ethyl acetate sedimentation concentration, kinyon carbol-fuchin stain, stool culture, enzyme immunoassay, culturing, morphometric study, gel electropho-resis and experimental infection of mice were done. The results showed that the central body cysts [CB], granular and multivacuolar forms isolated from symptomatic patients were larger than those from asymptomatic ones. The CB form was common compared to other forms and isolated from 104 cases. B. hominis infection was prevalent among males rather than females [60.5% versus 39.5%]. The clinical data showed that diarrhea was the most common symptom [58.9%]. The infection intensity had a direct relation with illness duration. The polyacrylamide gel electrophoresis showed that isolates from symptomatic and asymptomatic patients ranged between 24-130 kDa. All isolates showed similar banding patterns. Only minor differences was in low MW [30, 50 kDa] and in high MW [118 kDa] in samples from symptomatic patients. The histopathological examination of caecum, colon and small intestine of B. hominis mice infected from symptommatic patients showed infiltration with inflammatory cells and tissue invasion by the parasite

Echinococcosis granulosus in stray dogs and echino-IHAT in the hunters in Cairo, Egypt

A total of fifty stray dogs of both sex and of different ages were examined for natural infection with Echinococcus granulosus after post-mortem. Three main intestinal helminthes were recovered. These were in descending order of abundance Dipylidium caninum, Toxocara canis and E. granulosus. The latter worm was demonstrated in eight of them [16%]. The sera of three out of 21 dog-hunters [14.3%] showed positive Echino IHAT. Two of the hunters suffered Enterobius vermicularis and one of them had Taenia saginata as well. But, the abdominal X-ray of the two hunters was more or less normal and did not show any hydatid cyst

Effect of different therapeutic measures on nocturnal leg cramps for patients with varicose veins

To assess the effect of different therapeutic measures for nocturnal leg cramps on patients with varicose veins. The study was conducted at the out-patients clinics in El-Demerdash Hospital which is affiliated to Ain Shams University. The sample included 80 adult and old age patients from both genders with varicose veins and have developed nocturnal leg cramps. Tools of data collection consisted of: 1] A pre-designed questionnaires which includes patient's demographic data, frequency of leg cramps and patients knowledge, 2] exercise record, 3] diary record, 4] symptoms development sheet, and 5] information sheet. Revealed that, more than half of the sample had 60 years of age and more. Significant differences were found between pre / last follow-up tests among the four groups about diet knowledge and exercise control. Regarding outcome measures, there were gradual improvements in the four groups in post and follow-up tests. In addition the mean difference was lower in G1 [treatment group]. Diet and exercise therapy adding to pharmacological treatment as a therapeutic measure could be used in reducing nocturnal leg cramps for patients with varicose veins. Further studies are needed to elucidate the effect of other therapeutic measures on preventing nocturnal leg cramps

Role of some inflammatory markers in recent ischemic stroke

The onset of cerebral ischemia triggers a cascade of pro-inflammatory molecular and cellular events. Clinical studies suggest that the strength of this acute response is important in early and late clinical outcomes, early clinical worsening, and extent of brain damage. The aim of this work was to estimate the. role of some inflammatory markers in recent ischemic stroke, and to correlate these inflammatory markers with the short term outcome. Twenty sex patients presented with recent history of hemiplegia within 24 hours were included. The patient group was planned to contain 13 patients with the age between 20 and <40years and 13 patients with the age between 40 and 60 years. 15 subjects, [age and sex matched to the patients] were included in the study as control Neurological deficits were rated by Scandinavian Stroke Scale. Clinical assessments and serum levels of the inflammatory markers, Neopterin C -Reactive Protein [CRP], Tumor Necrosis Factor-alpha [TNF-alpha], Complement 4 [C-4], Interleukin-8 [IL-8], and Neopterin, were done at the time of admission, day 3, and day 7 from the stroke onset. Serum levels of neopterin started to increase from the 3 rd day and remained high to the end of the first week from the onset of the stroke. The increase was more obvious in the young aged patients. Serum levels of IL-8, raised rapidly in the acute phase of the stroke and then gradually decreased through the first wee and but still higher than the base line of the total patients and control. Serum levels of TNF-alpha and CRP had rapid significant increase from the first day to reach maximum levels in the 3 rd day and still significantly high till the end of the first week Serum CRP levels were higher in the old age group while serum C4 levels decreased from the 1 st day then gradually increased to reach maximum levels in the 7 th day, but still significantly lower than the control group. Also, there were statistically positive correlations between serum levels of neopterin and C-4 in the 3 rd sample with the Scandinavian scale in the 3 rd assessment. Brain ischemia induced an inflammatory cascade by the increase in serum levels of neopterin, IL-8, TNF-alpha, CRP and decrease in C4. This inflammatory response continued through the first week by the increase in the levels of complement -4. The inflammatory response was more obvious in the young aged patients. There were positive correlations between serum levels of neopterin, and C-4 with the short-term outcome of the stroke patients

Does phototherapy induce an oxidative stress in preterm neonates?

Of this study was to investigate whether phototherapy leads to oxidative stress in preterm newborns. Lipid peroxidation products as indicated by the thiobarbituric acid reacting substances [TBARS] in blood and urinary 8-Hydroxydeoxyguanosine [8-OHdG] as a protein peroxidation product in urine were assessed before and after exposure to phototherapy. Meanwhile, antioxidant activity in terms of plasma vitamin E and erythrocyte-glutathione peroxidase [GSH-PX] was assessed. The study group enrolled 24 preterm infants with physiological hyperbilirubinemia categorized according to the used modality of phototherapy into single and double phototherapy groups. Their mean gestational age was 31.22 +/- 2.63 weeks, and birth weight was 2.175 +/- 0.86 kg. Blood samples were collected immediately before and after 72 hours of phototherapy. Samples were analyzed for total serum bilirubin [TSB], serum albumin, blood TBARS, plasma vitamin E and erythrocyte-GSH-PX. Urine samples were collected before and after phototherapy for analysis of 8-OHdG. Levels of blood TBARS, Urine 8-OHdG were significantly elevated after phototherapy while plasma vitamin E and erythrocyte GSH-PX did not significantly change. Blood TBARS showed a negative correlation to TSB before phototherapy. The percent increase in serum TBARS or Urine 8-OHdG after phototherapy did not significantly correlate to gestational age or birth weight. Phototherapy induces oxidative stress in preterm neonates with unconjugated hyperbilirubinemia, regardless of their birth weight or gestational age. In face of this stress, antioxidant defense may be inadequate, requiring vitamin E supplementation. No significant photo-oxidant hazard is added in proceeding with double phototherapy in neonates under single phototherapy